LD w/ meal 11 11 two 7 2 11 two 9 2 9 2Matrix 0.eight 1.five 1.five 1.six 1.6 1.6 1.6 1.6 High High Higher High Higher Close to optimal Higher Bdln high Bdln high High Higher Bdln high Higher Optimal High Incredibly high ,50 50 ,50 .50 Sterol ester Free of charge sterols Stanol ester Sterol esters ,50 ,50 ,50 50 ,50 Sterol esters Sterol esters Sterol esters Sterol esters Stanol esters NR NR ,50 ,50 .50 ,50 .50 Free sterol Totally free sterol Sterol esters Sterol esters Sterol esters Sterol esters Stanol ester 1.six 1.eight 2 2 two 6 five 2 ten 2 9 22Design D NS High Male .50 Stanol estersPS g/d dose Baseline LDLc Sex Sort PS PS plant source (26) a (44) a (44) b (39) e (39) b (39) a (43) a (26) b (41) (40) (57) b (77) b (27) a (77) a (70) (26) c (25) aReported LDLcReferenceMargarine 2 two NR NR NR 2 2/3 two two two NR 2 NR NR 2/3 8 9 224wk crossoverMargarine Margarine Margarine Margarine Margarine Margarine Margarine LD BD NR NR BD NR NR w/ meal NR13wk parallel 26wk parallel 3wk parallel 3wk parallel 3wk parallel three.5wk crossover 4wk crossoverMargarine Margarine Margarine Margarine Margarine two two.1 two.four two.52wk parallel 3wk crossover 3wk crossover 4wk crossover 4wk parallelMargarine Margarine Margarine NR4wk crossover 3wk crossover 4wk crossoverMargarine4wk crossoverMargarine Margarine Margarine6wk crossover 6wk crossover 8wk crossover eight 10 22NR NR NR Bdln high Bdln higher Very highNR NR NR2.five 2.5 two.0 0 ,Stanol esters Stanol esters Sterol esters(45) a (45) b (25) bMargarine Margarine Margarine Margarine 15 12 two ten 223wk 3wk 3wk 4wk 2 2 two two 2 two 2/3 3 three BLD BLD three.8 4 NR NR LD LD LD LD w/ meal 3 three three.two three.two three.2 3.two three.2 12 11 NS NS two 13 two ten 22parallel parallel parallel parallelNR NR NRw/ meal w/ meal w/ meal BLD3 three 3High High Higher Bdln higher Higher Higher Bdln higher Bdln high Bdln higher Near optimal Higher 15 13 Near optimal Near optimal,50 ,50 .50 ,50 NR NR 50 50 50 ,50 .50 ,50 ,Sterol esters Sterol esters Sterol esters Stanol esters No cost sterol Totally free sterol Sterol esters Sterol esters Sterol esters Sterol esters Stanol esters Stanol esters Stanol esters(39) d (39) f (39) c (27) b (44) c (44) d (42) b (42) c (42) a (43) b (26) d (24) a (24) b (Continued)Margarine Margarine Margarine Margarine Margarine Margarine Margarine12wk parallel 26wk parallel three.5wk crossover three.5wk crossover 3.5wk crossover 3.5wk crossover 4wk crossoverPhytosterols and also the food matrixMargarine Margarine8wk parallel 8wk parallelSitostanol (77 ), campestanol (23 ) Wood Wood Tall oil, rapeseed oil Tall oil Soybean oil Soybean oil Sitostanol (76 ), campestanol (23 ) Soybean oil Soybean oil Vegetable oil Tall oil Sitostanol (60 ) Campestanol (40 ) Rapeseed oil Rice bran oil Sitostanol (76 ), campestanol (23 ) Soybean (60 ), rapeseed (30 ), sunflower (5 ) Tall oil Vegetable oil Soybean (60 ), rapeseed (30 ), sunflower (five ) Tall oil Tall oil, rapeseed oil Soybean oil Sitostanol (60 ), campestanol (40 ) Wood Wood Rice bran oil Sheanut oil Soybean oil Soybean oil Sitostanol (76 ), campestanol (23 ) Vegetable oil WoodTABLE 1 (Continued )Matrix 1 1 1 1 1 NR 1 1 1 two NR 1 1 2/3 1 1 2 two 2 two NR NR two 1 two 3 three two 2 NR2 2Design NR NR D D NR NR w/ meal L B w/ meal NR L w/o meal BLD L w/o meal BL BL NR w/ meal NR NR LD L w/o meal BLD BLD BD NR w/ or as a meal NR w/ or as a meal BLD 8.4-Chloro-5-cyano-7-azaindole Chemscene 9 four 2.4-Oxotetrahydrofuran-3-carbonitrile web four 11 8 17 Higher Higher Bdln high ,50 .PMID:33631791 50 ,50 Sterol esters Stanols Free of charge sterols stanols Vegetable oil Soybean oil Vegetable oil 0.three 0.four 0.5 0.five 0.5 3.four 1 1.six two 2 ,2 2.eight two.8 three 3.two 3.2 1.2 1.6 two 2 two 2 1.5 two.7 1.five 1.8 1.eight 2 three.2 two.4 12SC 2 SC 11 2 eight NS two SC 15 2 ten 2 four two 10 two ten 2 six 2 9 2 9 2 five two.