Product Name :
eIF1A Recombinant Rabbit Monoclonal Antibody [JE64-63]
Predicted band size :
16 kDa
Observed band size :
16 kDa
Synonyms:
eIF-1A antibody eIF-1A X isoform antibody eIF-4C antibody EIF1A antibody EIF1AP1 antibody EIF1AX antibody EIF4C antibody eukaryotic translation initiation factor 1A X-linked antibody eukaryotic translation initiation factor 1A, X chromosome antibody Eukaryotic translation initiation factor 1A, X-chromosomal antibody 展开
Function :
Eukaryotic translation initiation factor 1A, X-chromosomal (eIF1A) is a protein that in humans is encoded by the EIF1AX gene. This gene encodes an essential eukaryotic translation initiation factor.Formula of 2H-Pyrano[3,2-c]pyridin-4(3H)-one The protein is a component of the 43S pre-initiation complex (PIC), which mediates the recruitment of the small 40S ribosomal subunit to the 5′ cap of messenger RNAs.1220039-63-3 Price eIF1A is a small protein (17 kDa in budding yeast) and a component of the 43S preinitiation complexes (PIC).PMID:33560082 eIF1A binds near the ribosomal A-site, in a manner similar to the functionally related bacterial counterpart IF1. Mutations in this gene have been recurrently seen associated to cases of uveal melanoma with disomy 3. eIF1A is mutated in thyroid cancers. EIF1AX has been shown to interact with IPO13.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human eIF1A aa 51-100/144.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JE64-63
RRID:
AB_3072223
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 16 kDa
Positive control :
Jurkat cell lysate, HepG2 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, human colon carcinoma tissue.