Product Name :
Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59]
Predicted band size :
201 kDa
Observed band size :
200 kDa
Synonyms:
FLJ43106 antibody LAM antibody OTTHUMP00000158940 antibody OTTHUMP00000198394 antibody OTTHUMP00000198395 antibody PPP1R160 antibody Protein phosphatase 1, regulatory subunit 160 antibody tsc2 antibody TSC2_HUMAN antibody TSC4 antibody 展开
Function :
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human Tuberin aa 1760-1807 / 1807.1538623-41-4 Chemscene
Species reactivity:
Human, Mouse, Rat, Rat
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
SC05-59
RRID:
AB_3069893
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.6-(tert-Butoxy)-6-oxohexanoic acid structure Aliquot store at -20℃ or -80℃.PMID:33752567 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
201 kDa
Positive control :
HEK-293 cell lysate, HeLa cell lysate, LNCaP cell lysate, C6 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, MCF-7 cell lysates, human testis tissue, mouse testis tissue, mouse placenta tissue, rat testis tissue, HeLa.