Product Name :
2′-Hydroxyflavanone (CAS 17348-76-4)
Synonym :
Application :
CAS:
17348-76-4
Purity:
Molecular Weight:
240.25
Formula :
C15H12O3
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
SMILES:
C1C(OC2=CC=CC=C2C1=O)C3=CC=CC=C3O
References:
:2′-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma. | Nagaprashantha, LD., et al. 2011. Carcinogenesis. 32: 568-75. PMID: 213040512′-hydroxyflavanone inhibits prostate tumor growth through inactivation of AKT/STAT3 signaling and induction of cell apoptosis. | Wu, K., et al. 2014. Oncol Rep. 32: 131-8. PMID: 248599322′-Hydroxyflavanone: A promising molecule for kidney cancer prevention. | Singhal, SS., et al. 2015. Biochem Pharmacol. 96: 151-8. PMID: 259576602′-Hydroxyflavanone ameliorates mesenteric angiogenesis and portal-systemic collaterals in rats with liver fibrosis. | Hsin, IF., et al. 2016. J Gastroenterol Hepatol. 31: 1045-51. PMID: 26474184Hydroxyflavanone inhibits gastric carcinoma MGC-803 cell proliferation. | Zhang, H., et al. 2015. Int J Clin Exp Med. 8: 16955-9. PMID: 266292502′-Hydroxyflavanone: A novel strategy for targeting breast cancer. | Singhal, J., et al. 2017. Oncotarget. 8: 75025-75037. PMID: 290888422′-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer. | Nagaprashantha, LD., et al. 2018. Oncotarget. 9: 18053-18068. PMID: 297195902′-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76. | Singhal, J., et al. 2018. Mol Carcinog. 57: 1751-1762. PMID: 301364442′-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells. | Nagaprashantha, LD.6-Bromopyrazolo[1,5-a]pyridine site , et al.Price of Fmoc-D-Trp(Boc)-OH 2019.PMID:33555166 J Proteomics. 192: 233-245. PMID: 302484612′-Hydroxyflavanone activity in vitro and in vivo against wild-type and antimony-resistant Leishmania amazonensis. | Gervazoni, LFO., et al. 2018. PLoS Negl Trop Dis. 12: e0006930. PMID: 30521527Topical 2′-Hydroxyflavanone for Cutaneous Melanoma. | Bose, C., et al. 2019. Cancers (Basel). 11: PMID: 316150912′-Hydroxyflavanone inhibits the progression of pancreatic cancer cells and sensitizes the chemosensitivity of EGFR inhibitors via repressing STAT3 signaling. | Yue, Y., et al. 2020. Cancer Lett. 471: 135-146. PMID: 318119062′-Hydroxyflavanone prevents LPS-induced inflammatory response and cytotoxicity in murine macrophages. | Sonowal, H. and Ramana, KV. 2020. Toxicol In Vitro. 69: 104966. PMID: 32800949Efficacy of 2-Hydroxyflavanone in Rodent Models of Pain and Inflammation: Involvement of Opioidergic and GABAergic Anti-Nociceptive Mechanisms. | Khan, FA., et al. 2022. Molecules. 27: PMID: 36080199Analysis of 2′-hydroxyflavanone (2HF) in mouse whole blood by HPLC-MS/MS for the determination of pharmacokinetic parameters. | Gervazoni, LFO., et al. 2023. Front Chem. 11: 1016193. PMID: 36970405