Product Name :
TWEAK Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
APO 3 ligand antibody APO 3L antibody APO3 ligand antibody APO3/DR3 ligand antibody APO3L antibody DR3LG antibody MGC129581 antibody MGC20669 antibody secreted form antibody TNF-related weak inducer of apoptosis antibody 展开
Function :
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.4693-47-4 Price
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human TNFSF12.[2,2′-Bipyridine]-5,5′-dicarboxaldehyde Formula AA range:41-90
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33728841 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
27 kDa
Positive control :
Cerebellum,Fetal kidney,Fetal liver,Ovary,PCR rescued clone