Product Name :
Shank 2 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
AUTS17 antibody Cortactin binding protein 1 antibody Cortactin SH3 domain-binding protein antibody Cortactin-binding protein 1 antibody CortBP1 antibody CTTNBP1 antibody GKAP/SAPAP interacting protein antibody GKAP/SAPAP-interacting protein antibody KIAA1022 antibody Proline rich synapse associated protein 1 antibody 展开
Function :
This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif.Formula of 1951466-68-4 The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain.Price of 1209487-56-8 Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants.PMID:33606156
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human SHANK2. AA range:331-380
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
135 kDa
Positive control :
Brain,Epithelium,PCR rescued clones,