Product Name :
SWAP70 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
KIAA0640 70kDa AV235546 FLJ39540 HSPC321 SWA 70 protein SWAP 70 SWAP switching B-cell complex 70kDa subunit SWAP-70 SWAP70 展开
Function :
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human SWAP70 131-230/585
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep
Verify application:
WB, ELISA, IHC-P, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.Price of 5-Amino-3-methylindazole 4 0.6-Bromo-8-fluoroisoquinoline Purity 01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.PMID:33689574
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
69 KDa
Positive control :
Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue (PubMed:10681448). Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760).