Product Name :
RANTES Recombinant Rabbit Monoclonal Antibody [JM03-45]
Predicted band size :
Observed band size :
Synonyms:
Beta chemokine RANTES antibody Beta chemokine RANTES precursor antibody C C motif chemokine 5 antibody CCL 5 antibody CCL5 antibody CCL5_HUMAN antibody Chemokine (C C motif) ligand 5 antibody Chemokine CC Motif Ligand 5 antibody D17S136E antibody EoCP antibody 展开
Function :
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human RANTES aa 1-91.
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, IF-Cell, IF-Tissue
Coupling :
unconjugated
Clone number:
JM03-45
RRID:
AB_3070600
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2,4-Dimethylpyrimidin-5-ol uses Aliquot store at -20℃ or -80℃.Price of 3945-69-5 Avoid repeated freeze / thaw cycles.PMID:33616870
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 10 kDa
Positive control :
Mouse thymus lysates, Hela, HUVEC, human tonsil tissue, human placenta tissue.