Product Name :
PSD95 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Discs large homolog 4 antibody Disks large homolog 4 antibody DLG 4 antibody Dlg4 antibody DLG4_HUMAN antibody FLJ97752 antibody FLJ98574 antibody Human post synaptic density protein 95 antibody Post synaptic density protein 95 antibody Postsynaptic density protein 95 antibody 展开
Function :
PSD-95 is a member of the membrane-associated guanylate kinase(MAGUK) family. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the?clustering of receptors, ion channels, and associated signaling proteins.PSD-95 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density ofneurons,and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin,NMDA receptors,AMPA receptors, and potassium channels.It plays an important role in synaptic plasticity and the stabilization of synaptic changes during?long-term potentiation.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within N-terminal human PSD95.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3073317
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.ZH8651 Chemical name Aliquot store at -20℃ or -80℃.4,5-Dichlorophthalonitrile In stock Avoid repeated freeze / thaw cycles.PMID:33740121
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 80 kDa
Positive control :
A172 cell lysate, mouse brain tissue lysate, SHG-44 cell lysate, N2A cell lysate, rat brain tissue, mouse brain tissue.